University of California, Irvine
Anthony A. James, PhD is Donald Bren Professor of Microbiology & Molecular Genetics (School of Medicine) and Molecular Biology & Biochemistry (Ayala School of Biological Sciences) at the University of California, Irvine. He is a member of the National Academy of Sciences USA. His research group uses genetics as the basis for synthetic approaches to prevent transmission of mosquito-borne diseases. Contributions include the development of mosquito transgenesis procedures and engineered genes that interfere with malaria parasite development in mosquitoes. He collaborated also to develop approaches to prevent dengue virus transmission and a population-suppression strain based on flightless female mosquitoes. Most recently he collaborated to develop a gene-drive system to spread beneficial genes quickly through mosquito populations. Current work focuses on adapting the laboratory advances to tools that can be used in the field.